Barrett's oesophagus prevalence is estimated to affect between 2 and 7 million adults over 40 years of age in the United States. Each year ~ 86,000 new cases of Barrett's oesophagus are diagnosed.
The incidence of Barrett's oesophagus rises six-fold over the age of 50.
Barrett's and Oesophageal Adenocarcinoma
Patients with Barrett's oesophagus have an increased risk of developing oesophageal adenocarcinoma, 30 to 125 times higher than patients without this condition.
Every year, approximately 14,550 people in the U.S. are diagnosed with oesophageal cancer.
The incidence of oesophageal adenocarcinoma has risen approximately six-fold in the U.S. It is rising faster than breast cancer, prostate cancer, or melanoma.
Even with aggressive therapy, the 5-year survival rate from adenocarcinoma is only approximately 16%.
GORD and Barrett's oesophagus
Approximately up to 13% of Caucasian men over the age of 50, who have chronic reflux, will develop Barrett's oesophagus.
It's currently not possible on the basis of clinical presentation to distinguish GORD patients with Barrett's oesophagus from those in whom Barrett's oesophagus is not present.
In a study conducted by the Veteran Affairs and Stanford University in Palo Alto, CA 25% of patients > 50 years old without GORD symptoms were found to have Barrett's oesophagus.
GORD is common in the U.S. adult population. Symptoms of GORD, including heartburn, occur almost monthly in 50% of U.S. adults and weekly in almost 20%.